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Graphical presentation of CX-5461-mediated activation in the cytosolic DNA sensing pathway. cGAS binding into the cytosolic DNA activates the secondary messenger two,three-cGAMP using cGAS being a catalyst. Activated STING buds off the ER going into the perinuclear Golgi, exactly where it can be palmitoylated.Entirely, our info provide proof for yo

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